Ruby enables fully automated, label-free mechanical characterization of whole blood samples under standardized conditions.
Designed for translational and clinical research environments, Ruby minimizes operator dependency while maintaining single-cell resolution and full data transparency.
It translates real-time deformability cytometry into a streamlined, application-oriented platform.
Ruby is developed for laboratories working at the interface of research and medical application.
Key characteristics supporting translational use:
Standardized whole blood workflow
Minimal manual handling
Disposable closed microfluidic chip (RubyC)
No instrument contamination
Reproducible measurement conditions
Quantitative population-level statistics
Full single-cell traceability
Ruby enables consistent data generation across operators and laboratories — a prerequisite for future clinical validation studies.
Ruby is a fully integrated, standalone system for automated mechanical blood cell characterization.
Unlike the modular AcCellerator research platform, Ruby is:
A dedicated hematology research instrument
Fully automated from sample loading to result output
Delivered as a complete, calibrated system
Not compatible with AcCellerator add-ons
Ruby reduces technical complexity to a standardized workflow — enabling reproducible blood cell analysis across laboratories.
Ruby is operated using the dedicated single-use microfluidic chip RubyC, specifically designed for standardized whole blood analysis.
Measurement procedure:
Pipette one drop of whole blood into the designated RubyC inlet
Add two drops of measurement buffer into the corresponding buffer reservoirs
Insert the chip into the Ruby system
Press start
The system automatically performs:
Chip initialization and filling
Measurement region positioning
Autofocus
Real-time quality control
Population identification and classification
Data export
The dedicated RubyC chip contains the entire sample during measurement.
Whole blood never contacts internal instrument components.
This closed workflow:
Reduces contamination risk
Eliminates cleaning procedures
Simplifies multi-sample operation
Supports inter-laboratory standardization
After measurement, the chip is safely removed and disposed.
Ruby combines real-time mechanical phenotyping with automated morphological classification.
Key parameters:
Cell deformability by cell type (Erythrocytes, Neutrophils, Lymphocytes, Monocytes)
Cell size
Optical brightness and granularity
Morphological parameters from individual cell images
Population statistics and single-cell raw data export
Each measured cell is documented by image — enabling artifact detection and full data transparency.
~20,000 RBCs analyzed per measurement
~2,000 WBCs detected and characterized
Measurement time: approx. 15 minutes
Fully documented single-cell dataset
Daily calibration protocols included
Ruby delivers statistically robust results in a clinically relevant timeframe.
The integrated Ruby software provides:
Automated cell type classification
Real-time quality monitoring
Artifact filtering
Population statistics
Raw data export
Every measured cell remains traceable.
Mechanical blood cell phenotyping has demonstrated sensitivity to changes in cellular state.
Ruby translates this principle into a standardized and automated system designed to generate reproducible datasets suitable for longitudinal and multi-center studies.
It provides a technical foundation for future biomarker development and clinical validation workflows.
Single-use microfluidic chips
Integrated imaging system
Controlled pressure-driven flow
Fully enclosed and calibrated hardware
Delivered as complete standalone unit
Screen recording of the Ruby software during a full measurement cycle. After loading 20 µL of whole blood into a single-use microfluidic chip, the system automatically fills the channel, focuses on the measurement region, and begins real-time analysis. Approximately 20 000 erythrocytes (RBCs) are analyzed within seconds, followed by automated detection and characterization of approximately 2 000 leukocytes (WBCs). Continuous quality monitoring ensures reproducible and reliable results.
Pricing
The AcCellerator Ruby is 50 000 €.
(price only for business customers from academia within Europe, excl. VAT)
