Mechanical properties of cells are highly temperature-dependent.
Changes in temperature influence cytoskeletal dynamics, membrane viscosity, enzymatic activity and cell cycle progression.
The HeatModule enables real-time deformability cytometry (RT-DC) under precisely controlled thermal conditions — ensuring reproducibility, physiological relevance and experimental stability.
Designed as an integrated incubation system for the AcCellerator platform, it allows long-term measurements at defined temperatures up to 37 °C.
The HeatModule encapsulates large parts of the AcCellerator in a thermally controlled enclosure.
Key specifications:
Temperature range: ambient to 37 °C
Temperature stability: ±0.5 °C
Temperature accuracy: ±0.5 °C
300 W heating unit
Silent ventilation system for homogeneous air distribution
Temperature sensor positioned close to the sample
Automatic controller tuning
Overheat protection
Fast air circulation ensures rapid temperature recovery after opening the enclosure.
The HeatModule enables:
RT-DC measurements under physiological conditions
Controlled experiments on temperature-sensitive cell types
Long-term measurements without thermal drift
Reproducible comparison across experimental days
This is particularly relevant for:
stem cell research
immune cell activation studies
drug response profiling
mechanotransduction experiments
The HeatModule is fully compatible with:
AcCellerator systems based on Zeiss AxioObserver
existing installations
The package includes:
AcCellerator-compatible incubator box (Plexiglas and Makrolon)
installation and user training
No modification of core RT-DC measurement workflow is required.
The HeatModule enclosure provides a controlled micro-environment for temperature-sensitive RT-DC experiments.
The HeatModule is 15 000 €.
(price for academic customers within Europe, excl. VAT)
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