Publications related to or based on
real-time deformability cytometry  

Real-time fluorescence and deformability cytometry - flow cytometry goes mechanics

BioRxiv. preprint. 2017
Rosendahl P., Plak K., Jacobi A., Kraeter M., Toepfner N., Otto O., Herold C., Winzi M., Herbig M., Ge Y., Girardo S., Wagner K., Baum B., Guck J.

Detection Of Human Disease Conditions By Single-Cell Morpho-Rheological Phenotyping Of Whole Blood

BioRxiv. preprint. 2017
Töpfner N., Herold C., Otto O., Rosendahl P., Jacobi A., Kräter M., Stächele J., Menschner L., Herbig M., Ciuffreda L., Ranford-Cartwright L., Grzybek M., Coskun U., Reithuber E., Garriss G., Mellroth P., Henriques-Normark B., Tregay N., Suttorp M., Bornhäuser M., Chilvers E.R., Berner R., Guck J.

Toxicity and Immunogenicity in Murine Melanoma following Exposure to Physical Plasma-Derived Oxidants

Oxidative Medicine and Cellular Longevity. 2017
Bekeschus S., Rödder K., Fregin B., Otto O., Lippert M., Weltmann KD., Wende K., Schmidt A., Gandhirajan RK.

Numerical Simulation of Real-Time Deformability Cytometry To Extract Cell Mechanical Properties

ACS Biomater. Sci. Eng. 2017
Mokbel M., Mokbel D., Mietke A., Träber N., Girardo S., Otto O., Guck J., and Aland S.

Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells

Nature Communications. 2017
Tavares S., Vieira AF., Taubenberger AV., Araújo M., Martins NP., Brás-Pereira C., Polónia A., Herbig M., Barreto C., Otto O., Cardoso J., Pereira-Leal JB., Guck J., Paredes J., Janody F.

High-throughput cell mechanical phenotyping for label-free titration assays of cytoskeletal modifications.

Cytoskeleton. 2017
Golfier S., Rosendahl P., Mietke A., Herbig M., Guck J., Otto O.

Mapping of Deformation to Apparent Young's Modulus in Real-Time Deformability Cytometry 2017
Herold C.

Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion.

PNAS. 2017
Koch M., Wright KE., Otto O., Herbig M., Salinas ND., Tolia NH., Satchwell TJ., Guck J., Brooks NJ., Baum J.

Initiation of acute graft-versus-host disease by angiogenesis

Blood. 2017
Riesner K, Shi Y, Jacobi A, Kraeter M, Kalupa M, McGearey A, Mertlitz S, Cordes S, Schrezenmeier JF, Mengwasser J, Westphal S, Perez-Hernandez D, Schmitt C, Dittmar G, Guck J, Penack O.

V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy

Oncotarget. 2016
Bartel K, Winzi M, Ulrich M, Koeberle A, Menche D, Werz O, Müller R, Guck J, Vollmar AM, von Schwarzenberg K.

The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512

Mol Metab. 2016
Mziaut H, Mulligan B, Hoboth P, Otto O, Ivanova A, Herbig M, Schumann D, Hildebrandt T, Dehghany J, Sönmez A, Münster C, Meyer-Hermann M, Guck J, Kalaidzidis Y, Solimena M.

pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

eLife 2016
M. C. Munder, D. Midtvedt, T. Franzmann, E. Nüske, O. Otto, M. Herbig, E. Ulbricht, P. Müller, A. Taubenberger, S. Maharana, L. Malinovska, D. Richter, J. Guck, V. Zaburdaev and S. Alberti. A

Mechanical phenotyping of primary human skeletal stem cells in heterogeneous populations by real-time deformability cytometry

Integrative Biology 2016
M. Xavier, P. Rosendahl, M. Herbig, M. Kräter, D. Spencer, M. Bornhäuser, R. O. C. Oreffo, H. Morgan, J. Guck and O. Otto.

Myosin II Activity Softens Cells in Suspension

Biophysical Journal 2015
C. J. Chan, A. E. Ekpenyong, S. Golfier, W. Li, K. J. Chalut, O. Otto, J. Elgeti, J. Guck and F. Lautenschläger

Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia

Oncotarget 2015
M. Wobus, M. Bornhäuser, J. Guck, O. Otto, A. Jacobi, M. Kräter, C. Ortlepp, G. Ehninger, Ch. Thiede, and U. Oelschlägel

Extracting Cell Stiffness from Real-Time Deformability Cytometry: Theory and Experiment

Biophysical Journal 2015
A. Mietke, O. Otto, S. Girardo, P. Rosendahl, A. Taubenberger, S. Golfier, E. Ulbricht, S. Aaland, J. Guck and E. Fischer-Friedrich

Cell Mechanics: Combining Speed with Precision

Biophysical Journal 2015
Hans M. Wyss

Real-time deformability cytometry: on-the-fly cell mechanical phenotyping

Nature Methods 2015
O. Otto, Ph. Rosendahl, A. Mietke, S. Golfier, Ch. Herold, D. Klaue, S. Girardo, S. Pagliara, A. Ekpenyong, A. Jacobi, M. Wobus, N. Töpfner, U. F. Keyser, J. Mansfeld, E. Fischer-Friedrich, and J. Guck

Mechanics Meets Medicine

Science Translational Medicine 2013
Jochen Guck and Edwin R. Chilvers

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